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Sequential switching of binding partners on PCNA during in vitro Okazaki fragment maturation
The homotrimeric sliding clamp proliferating cell nuclear antigen (PCNA) mediates Okazaki fragment maturation through tight coordination of the activities of DNA polymerase δ (Pol δ), flap endonuclease 1 (FEN1) and DNA ligase I (Lig1). Little is known regarding the mechanism of partner switching on...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191785/ https://ncbi.nlm.nih.gov/pubmed/25228764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321349111 |
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