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PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins

In DNA replication, the leading strand is synthesized continuously, but lagging strand synthesis requires the complex, discontinuous synthesis of Okazaki fragments, and their subsequent joining. We have used a combination of in situ extraction and dual color photobleaching to compare the dynamic pro...

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Detalhes bibliográficos
Main Authors: Sporbert, Anje, Domaing, Petra, Leonhardt, Heinrich, Cardoso, M. Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156965/
https://ncbi.nlm.nih.gov/pubmed/15972794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki665
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