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Okazaki fragment maturation: nucleases take centre stage

Completion of lagging strand DNA synthesis requires processing of up to 50 million Okazaki fragments per cell cycle in mammalian cells. Even in yeast, the Okazaki fragment maturation happens approximately a million times during a single round of DNA replication. Therefore, efficient processing of Ok...

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Detalhes bibliográficos
Main Authors: Zheng, Li, Shen, Binghui
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030970/
https://ncbi.nlm.nih.gov/pubmed/21278448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjq048
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