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Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage

Human DNA polymerase δ (Pol δ) is involved in various DNA damage responses in addition to its central role in DNA replication. The Pol δ4 holoenzyme consists of four subunits, p125, p50, p68 and p12. It has been established that the p12 subunit is rapidly degraded in response to DNA damage by UV lea...

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Библиографические подробности
Главные авторы: Chea, Jennifer, Zhang, Sufang, Zhao, Hong, Zhang, Zhongtao, Lee, Ernest Y.C., Darzynkiewicz, Zbigniew, Lee, Marietta Y.W.T.
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419061/
https://ncbi.nlm.nih.gov/pubmed/22801543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21280
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