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(Un)folding mechanisms of adaptation to ER stress: lessons from aneuploidy

During stress, accumulation of misfolded proteins in the endoplasmic reticulum (ER) triggers activation of the adaptive mechanisms that restore protein homeostasis. One mechanism that eukaryotic cells use to respond to ER stress is through activation of the unfolded protein response (UPR) signaling...

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Detalles Bibliográficos
Publicado en:Curr Genet
Autores principales: Beaupere, Carine, Labunskyy, Vyacheslav M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421085/
https://ncbi.nlm.nih.gov/pubmed/30511161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-018-0914-9
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