Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast

The yeast genome becomes unstable during stress, which often results in adaptive aneuploidy, allowing rapid activation of protective mechanisms that restore cellular homeostasis. In this study, we performed a genetic screen in Saccharomyces cerevisiae to identify genome adaptations that confer resis...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Beaupere, Carine, Dinatto, Leticia, Wasko, Brian M., Chen, Rosalyn B., VanValkenburg, Lauren, Kiflezghi, Michael G., Lee, Mitchell B., Promislow, Daniel E. L., Dang, Weiwei, Kaeberlein, Matt, Labunskyy, Vyacheslav M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156608/
https://ncbi.nlm.nih.gov/pubmed/30185560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804264115
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