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TIS11 AND CTH1 DEFICIENCY LEADS TO METABOLIC REPROGRAMING AND EXTENDS REPLICATIVE LIFESPAN IN YEAST

Iron (Fe) serves as a cofactor for many enzymes involved in metabolism and mitochondrial function. Dysregulation of Fe homeostasis has been implicated in the pathogenesis of numerous age-related human diseases. However, the role of Fe bioavailability in regulation of lifespan and how aging affects F...

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Detalhes bibliográficos
Publicado no:Innov Aging
Main Authors: Beaupere, C, Wasko, B, Kaeberlein, Matt, Labunskyy, V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6227040/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.1610
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