Buffering the pH of the culture medium does not extend yeast replicative lifespan

During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival.  As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standard conditions in synthetic medium.  In this study...

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Bibliographische Detailangaben
Hauptverfasser: Wasko, Brian M, Carr, Daniel T, Tung, Herman, Doan, Ha, Schurman, Nathan, Neault, Jillian R, Feng, Joey, Lee, Janet, Zipkin, Ben, Mouser, Jacob, Oudanonh, Edward, Nguyen, Tina, Stetina, Torin, Shemorry, Anna, Lemma, Mekedes, Kaeberlein, Matt
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000Research 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886788/
https://ncbi.nlm.nih.gov/pubmed/24555104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-216.v1
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