Buffering the pH of the culture medium does not extend yeast replicative lifespan

During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival.  As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standard conditions in synthetic medium.  In this study...

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Detalhes bibliográficos
Main Authors: Wasko, Brian M, Carr, Daniel T, Tung, Herman, Doan, Ha, Schurman, Nathan, Neault, Jillian R, Feng, Joey, Lee, Janet, Zipkin, Ben, Mouser, Jacob, Oudanonh, Edward, Nguyen, Tina, Stetina, Torin, Shemorry, Anna, Lemma, Mekedes, Kaeberlein, Matt
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886788/
https://ncbi.nlm.nih.gov/pubmed/24555104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-216.v1
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