Buffering the pH of the culture medium does not extend yeast replicative lifespan

During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival.  As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standard conditions in synthetic medium.  In this study...

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Main Authors: Wasko, Brian M, Carr, Daniel T, Tung, Herman, Doan, Ha, Schurman, Nathan, Neault, Jillian R, Feng, Joey, Lee, Janet, Zipkin, Ben, Mouser, Jacob, Oudanonh, Edward, Nguyen, Tina, Stetina, Torin, Shemorry, Anna, Lemma, Mekedes, Kaeberlein, Matt
格式: Artigo
語言:Inglês
出版: F1000Research 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886788/
https://ncbi.nlm.nih.gov/pubmed/24555104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-216.v1
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