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CAN1 Arginine Permease Deficiency Extends Yeast Replicative Lifespan via Translational Activation of Stress Response Genes

Transcriptional regulation plays an important role in the control of gene expression during aging. However, translation efficiency likely plays an equally important role in determining protein abundance, but has been relatively under studied in this context. Here we used RNA-seq and ri-bosome profil...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Beaupere, Carine, Wasko, Brian M., Lorusso, Jared, Kennedy, Brian K., Kaeberlein, Matt, Labunskyy, Vyacheslav M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327506/
https://ncbi.nlm.nih.gov/pubmed/28228255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.01.077
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