Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast

The yeast genome becomes unstable during stress, which often results in adaptive aneuploidy, allowing rapid activation of protective mechanisms that restore cellular homeostasis. In this study, we performed a genetic screen in Saccharomyces cerevisiae to identify genome adaptations that confer resis...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Beaupere, Carine, Dinatto, Leticia, Wasko, Brian M., Chen, Rosalyn B., VanValkenburg, Lauren, Kiflezghi, Michael G., Lee, Mitchell B., Promislow, Daniel E. L., Dang, Weiwei, Kaeberlein, Matt, Labunskyy, Vyacheslav M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156608/
https://ncbi.nlm.nih.gov/pubmed/30185560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804264115
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker