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(Un)folding mechanisms of adaptation to ER stress: lessons from aneuploidy

During stress, accumulation of misfolded proteins in the endoplasmic reticulum (ER) triggers activation of the adaptive mechanisms that restore protein homeostasis. One mechanism that eukaryotic cells use to respond to ER stress is through activation of the unfolded protein response (UPR) signaling...

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Detalles Bibliográficos
Publicado en:Curr Genet
Main Authors: Beaupere, Carine, Labunskyy, Vyacheslav M.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421085/
https://ncbi.nlm.nih.gov/pubmed/30511161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-018-0914-9
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