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(Un)folding mechanisms of adaptation to ER stress: lessons from aneuploidy

During stress, accumulation of misfolded proteins in the endoplasmic reticulum (ER) triggers activation of the adaptive mechanisms that restore protein homeostasis. One mechanism that eukaryotic cells use to respond to ER stress is through activation of the unfolded protein response (UPR) signaling...

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Bibliografiske detaljer
Udgivet i:Curr Genet
Main Authors: Beaupere, Carine, Labunskyy, Vyacheslav M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421085/
https://ncbi.nlm.nih.gov/pubmed/30511161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-018-0914-9
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