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Role of Aldose Reductase in Diabetes-Induced Retinal Microglia Activation

Diabetes-induced hyperglycemia plays a key pathogenic role in degenerative retinal diseases. In diabetic hyperglycemia, aldose reductase (AR) is elevated and linked to the pathogenesis of diabetic retinopathy (DR) and cataract. Retinal microglia (RMG), the resident immune cells in the retina, are th...

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Bibliografiske detaljer
Udgivet i:Chem Biol Interact
Main Authors: Chang, Kun-Che, Shieh, Biehuoy, Petrash, J. Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421082/
https://ncbi.nlm.nih.gov/pubmed/30682331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.01.020
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