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Diabetes-Independent Retinal Phenotypes in an Aldose Reductase Transgenic Mouse Model

Aldose reductase (AR), the first and rate-limiting enzyme of the polyol pathway, has been implicated in the onset and development of the ocular complications of diabetes, including cataracts and retinopathy. Despite decades of research conducted to address possible mechanisms, questions still persis...

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Publicado en:Metabolites
Autores principales: Petrash, Jonathan Mark, Shieh, Biehuoy, Ammar, David A., Pedler, Michelle G., Orlicky, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305400/
https://ncbi.nlm.nih.gov/pubmed/34357344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11070450
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