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Diabetes-Independent Retinal Phenotypes in an Aldose Reductase Transgenic Mouse Model

Aldose reductase (AR), the first and rate-limiting enzyme of the polyol pathway, has been implicated in the onset and development of the ocular complications of diabetes, including cataracts and retinopathy. Despite decades of research conducted to address possible mechanisms, questions still persis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Metabolites
Egile Nagusiak: Petrash, Jonathan Mark, Shieh, Biehuoy, Ammar, David A., Pedler, Michelle G., Orlicky, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305400/
https://ncbi.nlm.nih.gov/pubmed/34357344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11070450
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