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Role of Aldose Reductase in Diabetes-Induced Retinal Microglia Activation

Diabetes-induced hyperglycemia plays a key pathogenic role in degenerative retinal diseases. In diabetic hyperglycemia, aldose reductase (AR) is elevated and linked to the pathogenesis of diabetic retinopathy (DR) and cataract. Retinal microglia (RMG), the resident immune cells in the retina, are th...

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Detalles Bibliográficos
Publicado en:Chem Biol Interact
Main Authors: Chang, Kun-Che, Shieh, Biehuoy, Petrash, J. Mark
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421082/
https://ncbi.nlm.nih.gov/pubmed/30682331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.01.020
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