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Aldose Reductase Inhibition Alleviates Hyperglycemic Effects on Human Retinal Pigment Epithelial Cells

Chronic hyperglycemia is an important risk factor involved in the onset and progression of diabetic retinopathy (DR). Among other effectors, aldose reductase (AR) has been linked to the pathogenesis of this degenerative disease. The purpose of this study was to investigate whether the novel AR inhib...

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Bibliografiske detaljer
Udgivet i:Chem Biol Interact
Main Authors: Chang, Kun-Che, Snow, Anson, LaBarbera, Daniel V., Petrash, J. Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402120/
https://ncbi.nlm.nih.gov/pubmed/25451566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.10.007
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