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Aldose Reductase Inhibition Alleviates Hyperglycemic Effects on Human Retinal Pigment Epithelial Cells

Chronic hyperglycemia is an important risk factor involved in the onset and progression of diabetic retinopathy (DR). Among other effectors, aldose reductase (AR) has been linked to the pathogenesis of this degenerative disease. The purpose of this study was to investigate whether the novel AR inhib...

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發表在:Chem Biol Interact
Main Authors: Chang, Kun-Che, Snow, Anson, LaBarbera, Daniel V., Petrash, J. Mark
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402120/
https://ncbi.nlm.nih.gov/pubmed/25451566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.10.007
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