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Aldose Reductase Inhibition Alleviates Hyperglycemic Effects on Human Retinal Pigment Epithelial Cells

Chronic hyperglycemia is an important risk factor involved in the onset and progression of diabetic retinopathy (DR). Among other effectors, aldose reductase (AR) has been linked to the pathogenesis of this degenerative disease. The purpose of this study was to investigate whether the novel AR inhib...

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Библиографические подробности
Опубликовано в: :Chem Biol Interact
Главные авторы: Chang, Kun-Che, Snow, Anson, LaBarbera, Daniel V., Petrash, J. Mark
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402120/
https://ncbi.nlm.nih.gov/pubmed/25451566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.10.007
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