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Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues

Aldose reductase (AR) catalyzes the reduction of toxic lipid aldehydes to their alcohol products and mediates inflammatory signals triggered by lipopolysaccharide (LPS). Beta-glucogallin (BGG), a recently described AR inhibitor, was purified from extracts of the Indian gooseberry (Emblica officinali...

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Autors principals: Chang, Kun-Che, Laffin, Brian, Ponder, Jessica, Énzsöly, Anna, Németh, János, LaBarbera, Daniel V., Petrash, J. Mark
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656825/
https://ncbi.nlm.nih.gov/pubmed/23247009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.12.001
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