Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues

Aldose reductase (AR) catalyzes the reduction of toxic lipid aldehydes to their alcohol products and mediates inflammatory signals triggered by lipopolysaccharide (LPS). Beta-glucogallin (BGG), a recently described AR inhibitor, was purified from extracts of the Indian gooseberry (Emblica officinali...

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Detalhes bibliográficos
Main Authors: Chang, Kun-Che, Laffin, Brian, Ponder, Jessica, Énzsöly, Anna, Németh, János, LaBarbera, Daniel V., Petrash, J. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656825/
https://ncbi.nlm.nih.gov/pubmed/23247009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.12.001
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