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Aldose Reductase Inhibition Prevents Endotoxin-Induced Inflammatory Responses in Retinal Microglia

PURPOSE. Retinal microglia become activated in diabetes and produce pro-inflammatory molecules associated with changes in retinal vasculature and increased apoptosis of retinal neurons and glial cells. We sought to determine if the action of aldose reductase (AR), an enzyme linked to the pathogenesi...

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Bibliografski detalji
Glavni autori: Chang, Kun-Che, Ponder, Jessica, LaBarbera, Daniel V., Petrash, J. Mark
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010364/
https://ncbi.nlm.nih.gov/pubmed/24677107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13487
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