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Aldose Reductase Inhibition Alleviates Hyperglycemic Effects on Human Retinal Pigment Epithelial Cells

Chronic hyperglycemia is an important risk factor involved in the onset and progression of diabetic retinopathy (DR). Among other effectors, aldose reductase (AR) has been linked to the pathogenesis of this degenerative disease. The purpose of this study was to investigate whether the novel AR inhib...

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Pubblicato in:Chem Biol Interact
Autori principali: Chang, Kun-Che, Snow, Anson, LaBarbera, Daniel V., Petrash, J. Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402120/
https://ncbi.nlm.nih.gov/pubmed/25451566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.10.007
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