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Diabetes-Independent Retinal Phenotypes in an Aldose Reductase Transgenic Mouse Model

Aldose reductase (AR), the first and rate-limiting enzyme of the polyol pathway, has been implicated in the onset and development of the ocular complications of diabetes, including cataracts and retinopathy. Despite decades of research conducted to address possible mechanisms, questions still persis...

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Podrobná bibliografie
Vydáno v:Metabolites
Hlavní autoři: Petrash, Jonathan Mark, Shieh, Biehuoy, Ammar, David A., Pedler, Michelle G., Orlicky, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305400/
https://ncbi.nlm.nih.gov/pubmed/34357344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11070450
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