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Diabetes-Independent Retinal Phenotypes in an Aldose Reductase Transgenic Mouse Model

Aldose reductase (AR), the first and rate-limiting enzyme of the polyol pathway, has been implicated in the onset and development of the ocular complications of diabetes, including cataracts and retinopathy. Despite decades of research conducted to address possible mechanisms, questions still persis...

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Detaylı Bibliyografya
Yayımlandı:Metabolites
Asıl Yazarlar: Petrash, Jonathan Mark, Shieh, Biehuoy, Ammar, David A., Pedler, Michelle G., Orlicky, David J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305400/
https://ncbi.nlm.nih.gov/pubmed/34357344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11070450
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