A carregar...
CRISPR-Cas9 circular permutants as programmable scaffolds for genome modification
The ability to engineer natural proteins is pivotal to a future, pragmatic biology. CRISPR proteins have revolutionized genome modification, yet the CRISPR-Cas9 scaffold is not ideal for fusions or activation by cellular triggers. Here we show that topological rearrangement of Cas9 using circular pe...
Na minha lista:
| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6414052/ https://ncbi.nlm.nih.gov/pubmed/30633905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.052 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|