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Cornerstones of CRISPR-Cas in drug development and therapy

The recent development of CRISPR-Cas systems as easily accessible and programmable tools for genome editing and regulation is spurring a revolution in biology. Paired with the rapid expansion of personalized and reference genomic sequence information, technologies based on CRISPR-Cas are enabling ne...

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Detalles Bibliográficos
Publicado en:Nat Rev Drug Discov
Main Authors: Fellmann, Christof, Gowen, Benjamin G., Lin, Pei-Chun, Doudna, Jennifer A., Corn, Jacob E.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459481/
https://ncbi.nlm.nih.gov/pubmed/28008168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.238
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