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Genomes in Focus: Development and Applications of CRISPR-Cas9 Imaging Technologies
The discovery of the CRISPR-Cas9 endonuclease has enabled facile genome editing in living cells and organisms. Catalytically inactive Cas9 (dCas9) retains the ability to bind DNA in an RNA-guided fashion, and has additionally been explored as a tool for transcriptional modulation, epigenetic editing...
Gorde:
| Argitaratua izan da: | Angew Chem Int Ed Engl |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6014596/ https://ncbi.nlm.nih.gov/pubmed/29080263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201709201 |
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