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Development and Potential Applications of CRISPR-Cas9 Genome Editing Technology in Sarcoma
Sarcomas include some of the most aggressive tumors and typically respond poorly to chemotherapy. In recent years, specific gene fusion/mutations and gene over-expression/activation have been shown to drive sarcoma pathogenesis and development. These emerging genomic alterations may provide targets...
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| Vydáno v: | Cancer Lett |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4772675/ https://ncbi.nlm.nih.gov/pubmed/26806808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.01.030 |
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