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Development and Potential Applications of CRISPR-Cas9 Genome Editing Technology in Sarcoma

Sarcomas include some of the most aggressive tumors and typically respond poorly to chemotherapy. In recent years, specific gene fusion/mutations and gene over-expression/activation have been shown to drive sarcoma pathogenesis and development. These emerging genomic alterations may provide targets...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Liu, Tang, Shen, Jacson K., Li, Zhihong, Choy, Edwin, Hornicek, Francis J., Duan, Zhenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772675/
https://ncbi.nlm.nih.gov/pubmed/26806808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.01.030
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