Targeting programmed cell death ligand 1 by CRISPR/Cas9 in osteosarcoma cells

Programmed cell death ligand 1 (PD-L1) is a transmembrane protein that is expressed on tumor cells that suppresses the T cell-mediated immune response. Therapies targeting the PD-L1 pathway promote anti-tumor immunity and have shown promising results in some types of cancers. However, the functional...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Liao, Yunfei, Chen, Lulu, Feng, Yong, Shen, Jacson, Gao, Yan, Cote, Gregory, Choy, Edwin, Harmon, David, Mankin, Henry, Hornicek, Francis, Duan, Zhenfeng
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444742/
https://ncbi.nlm.nih.gov/pubmed/28415820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16326
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