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DRONE: Direct tracking of DNA cytidine deamination and other DNA modifying activities

Enzymes that catalyze DNA modifying activities including cytidine deamination and cytosine methylation play important biological roles and have been implicated pathologically in diseases such as cancer. Here, we report Direct Resolution of ONE dalton difference (DRONE), an UHPLC-based analytical met...

Ausführliche Beschreibung

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Veröffentlicht in:Anal Chem
Hauptverfasser: Sasaki, Tomoaki, Kudalkar, Shalley N., Bertoletti, Nicole, Anderson, Karen S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410358/
https://ncbi.nlm.nih.gov/pubmed/30256094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01405
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