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Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
The expression of activation-induced cytidine deaminase (AID) is prerequisite to a “trifecta” of key molecular events in B cells: class-switch recombination and somatic hypermutation in humans and mice and gene conversion in chickens. Although this critically important enzyme shares common sequence...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153055/ https://ncbi.nlm.nih.gov/pubmed/12651944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730835100 |
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