Regulation of Activation-Induced Cytidine Deaminase DNA Deamination Activity in B Cells by Serine-38 Phosphorylation

Human and mouse immunoglobulin (Ig) genes are diversified in mature B cells by distinct processes known as Ig heavy chain class switch recombination (CSR) and Ig variable region exon somatic hypermutation (SHM). These DNA modification processes are initiated by activation-induced cytidine deaminase...

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Bibliografiset tiedot
Päätekijät: Basu, Uttiya, Franklin, Andrew, Schwer, Bjoern, Cheng, Hwei-Ling, Chaudhuri, Jayanta, Alt, Frederick W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540414/
https://ncbi.nlm.nih.gov/pubmed/19442251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0370561
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