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Regulation of Activation-Induced Cytidine Deaminase DNA Deamination Activity in B Cells by Serine-38 Phosphorylation
Human and mouse immunoglobulin (Ig) genes are diversified in mature B cells by distinct processes known as Ig heavy chain class switch recombination (CSR) and Ig variable region exon somatic hypermutation (SHM). These DNA modification processes are initiated by activation-induced cytidine deaminase...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540414/ https://ncbi.nlm.nih.gov/pubmed/19442251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0370561 |
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