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Post-translational regulation of activation-induced cytidine deaminase

The assembled immunoglobulin genes in the B cells of mice and humans are altered by distinct processes known as class switch recombination (CSR) and somatic hypermutation, leading to diversification of the antibody repertoire. These two DNA modification processes are initiated by the B cell-specific...

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書目詳細資料
Main Authors: Basu, Uttiya, Franklin, Andrew, Alt, Frederick W.
格式: Artigo
語言:Inglês
出版: The Royal Society 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660916/
https://ncbi.nlm.nih.gov/pubmed/19010772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0194
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