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The complex regulation and function of activation-induced cytidine deaminase (AID)
Activation-induced cytidine deaminase (AID) instigates mutations and DNA breaks in Ig genes undergoing somatic hypermutation (SHM) and class switch recombination (CSR) during B cell activation in response to immunization and infection. This review discusses how AID expression and activity are regula...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090464/ https://ncbi.nlm.nih.gov/pubmed/21493144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.03.003 |
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