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Negative regulation of activation-induced cytidine deaminase in B cells
Both class switch recombination (CSR) and somatic hypermutation (SHM) of the Ig genes require the activity of activation-induced cytidine deaminase (AID). Expression of AID is restricted to B cells in the germinal centers of the lymphoid organs, where activated B cells undergo CSR and SHM. We previo...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413812/ https://ncbi.nlm.nih.gov/pubmed/16477013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510970103 |
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