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De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
Activation-induced cytidine deaminase (AID) is required for class-switch recombination (CSR), somatic hypermutation, and gene conversion of Ig genes. Although AID has sequence similarity to an RNA-editing enzyme Apobec-1, how AID functions in CSR and somatic hypermutation is unknown. Because involve...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The National Academy of Sciences
2003
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151392/ https://ncbi.nlm.nih.gov/pubmed/12591955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437710100 |
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