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Post-translational regulation of activation-induced cytidine deaminase
The assembled immunoglobulin genes in the B cells of mice and humans are altered by distinct processes known as class switch recombination (CSR) and somatic hypermutation, leading to diversification of the antibody repertoire. These two DNA modification processes are initiated by the B cell-specific...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Royal Society
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660916/ https://ncbi.nlm.nih.gov/pubmed/19010772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0194 |
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