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The Transcription Elongation Complex Directs Activation-Induced Cytidine Deaminase-Mediated DNA Deamination
Activation-induced cytidine deaminase (AID) is a single-stranded DNA deaminase required for somatic hypermutation of immunoglobulin (Ig) genes, a key process in the development of adaptive immunity. Transcription provides a single-stranded DNA substrate for AID, both in vivo and in vitro. We present...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489098/ https://ncbi.nlm.nih.gov/pubmed/16705187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02375-05 |
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