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AID Mediates Hypermutation by Deaminating Single Stranded DNA
Activation-induced deaminase (AID) is a protein indispensable for the diversification of immunoglobulin (Ig) genes by somatic hypermutation (SHM), class switch recombination (CSR), and gene conversion. To date, the precise role of AID in these processes has not been determined. Here we demonstrate t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193777/ https://ncbi.nlm.nih.gov/pubmed/12756266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030481 |
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