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AID Mediates Hypermutation by Deaminating Single Stranded DNA

Activation-induced deaminase (AID) is a protein indispensable for the diversification of immunoglobulin (Ig) genes by somatic hypermutation (SHM), class switch recombination (CSR), and gene conversion. To date, the precise role of AID in these processes has not been determined. Here we demonstrate t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dickerson, Sarah K., Market, Eleonora, Besmer, Eva, Papavasiliou, F. Nina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193777/
https://ncbi.nlm.nih.gov/pubmed/12756266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030481
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