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Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption

BACKGROUND & AIMS: The nuclear receptor subfamily 0 group B member 2 (NR0B2, also called SHP) is expressed at high levels in liver and intestine. Postprandial fibroblast growth factor 19 (human FGF19, mouse FGF15) signaling increases the transcriptional activity of SHP. We studied the functions...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Gastroenterology
Egile Nagusiak: Kim, Young-Chae, Byun, Sangwon, Seok, Sunmi, Guo, Grace, Xu, H. Eric, Kemper, Byron, Kemper, Jongsook Kim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409196/
https://ncbi.nlm.nih.gov/pubmed/30521806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.11.061
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