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A role for NPC1 and NPC2 in intestinal cholesterol absorption – the hypothesis gutted
Dietary and biliary cholesterol are taken up by intestinal epithelial cells and transported to the endoplasmic reticulum. At the endoplasmic reticulum, cholesterol is esterified, packaged into chylomicrons and secreted into the lymph for delivery to the bloodstream. NPC1L1 (Niemann–Pick C1-like 1) i...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2049072/ https://ncbi.nlm.nih.gov/pubmed/17956226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071340 |
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