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Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?
NPC1L1 (Niemann–Pick C1-like 1), the pharmacological target of the cholesterol-uptake inhibitor ezetimibe, is a transporter localized on the brush border of enterocytes. Although this protein plays a key role in intestinal uptake of sterols, multiple molecular events that underlie intestinal cholest...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Portland Press Ltd.
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2049080/ https://ncbi.nlm.nih.gov/pubmed/17880278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071167 |
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