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Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?

NPC1L1 (Niemann–Pick C1-like 1), the pharmacological target of the cholesterol-uptake inhibitor ezetimibe, is a transporter localized on the brush border of enterocytes. Although this protein plays a key role in intestinal uptake of sterols, multiple molecular events that underlie intestinal cholest...

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Bibliografske podrobnosti
Main Authors: Dixit, Sayali S., Sleat, David E., Stock, Ann M., Lobel, Peter
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049080/
https://ncbi.nlm.nih.gov/pubmed/17880278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071167
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