Glial fibrillary acidic protein is elevated in the lysosomal storage disease classical late-infantile neuronal ceroid lipofuscinosis but is not a component of the storage material

Por XU, Su, SLEAT, David E., JADOT, Michel, LOBEL, Peter
Publicado em 2010

Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?

Por Dixit, Sayali S., Sleat, David E., Stock, Ann M., Lobel, Peter
Publicado em 2007

Genetic modulation of apoptotic pathways fails to alter disease course in tripeptidyl-peptidase 1 deficient mice

Por Kim, Kwi-Hye, Sleat, David E., Bernard, Ora, Lobel, Peter
Publicado em 2009

Dipeptidyl-peptidase I does not functionally compensate for the loss of tripeptidyl-peptidase I in the neurodegenerative disease late-infantile neuronal ceroid lipofuscinosis

Por Kim, Kwi-Hye, Pham, Christine T., Sleat, David E., Lobel, Peter
Publicado no Biochem J (2008)

Systemic Administration of Tripeptidyl Peptidase I in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis: Effect of Glycan Modification

Por Meng, Yu, Sohar, Istvan, Wang, Lingling, Sleat, David E., Lobel, Peter
Publicado em 2012

Potential Pitfalls and Solutions for Use of Fluorescent Fusion Proteins to Study the Lysosome

Por Huang, Ling, Pike, Douglas, Sleat, David E., Nanda, Vikas, Lobel, Peter
Publicado em 2014

Analysis of large-scale whole exome sequencing data to determine the prevalence of genetically-distinct forms of neuronal ceroid lipofuscinosis

Por Sleat, David E., Gedvilaite, Erika, Zhang, Yeting, Lobel, Peter, Xing, Jinchuan
Publicado no Gene (2016)

Inducible transgenic expression of tripeptidyl peptidase 1 in a mouse model of late-infantile neuronal ceroid lipofuscinosis

Por Nemtsova, Yuliya, Wiseman, Jennifer A., El-Banna, Mukarram, Lobel, Peter, Sleat, David E.
Publicado no PLoS One (2018)

Acid phosphatase 5 is responsible for removing the mannose 6-phosphate recognition marker from lysosomal proteins

Por Sun, Pengling, Sleat, David E., Lecocq, Michèle, Hayman, Alison R., Jadot, Michel, Lobel, Peter
Publicado em 2008

The mannose 6-phosphate glycoprotein proteome

Por Sleat, David E., Valle, Maria Cecilia Della, Zheng, Haiyan, Moore, Dirk F., Lobel, Peter
Publicado em 2008

Loss of Niemann-Pick C1 or C2 Protein Results in Similar Biochemical Changes Suggesting That These Proteins Function in a Common Lysosomal Pathway

Por Dixit, Sayali S., Jadot, Michel, Sohar, Istvan, Sleat, David E., Stock, Ann M., Lobel, Peter
Publicado em 2011

Large-volume Intrathecal Enzyme Delivery Increases Survival of a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

Por Xu, Su, Wang, Lingling, El-Banna, Mukarram, Sohar, Istvan, Sleat, David E, Lobel, Peter
Publicado em 2011

Classification of Subcellular Location by Comparative Proteomic Analysis of Native and Density-shifted Lysosomes

Por Della Valle, Maria Cecilia, Sleat, David E., Zheng, Haiyan, Moore, Dirk F., Jadot, Michel, Lobel, Peter
Publicado em 2011

Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late infantile neuronal ceroid lipofuscinosis

Por Sleat, David E., El-Banna, Mukarram, Sohar, Istvan, Kim, Kwi-Hye, Dobrenis, Kostantin, Walkley, Steven U., Lobel, Peter
Publicado em 2008

Proteomic analysis of mouse models of Niemann-Pick C disease reveals alterations in the steady-state levels of lysosomal proteins within the brain

Por Sleat, David E., Wiseman, Jennifer A., Sohar, Istvan, El –Banna, Mukarram, Zheng, Haiyan, Moore, Dirk F., Lobel, Peter
Publicado em 2012

A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration

Por Tyynelä, Jaana, Sohar, Istvan, Sleat, David E., Gin, Rosalie M., Donnelly, Robert J., Baumann, Marc, Haltia, Matti, Lobel, Peter
Publicado em 2000

Niemann-Pick Disease Type C: Spectrum of HE1 Mutations and Genotype/Phenotype Correlations in the NPC2 Group

Por Millat, Gilles, Chikh, Karim, Naureckiene, Saule, Sleat, David E., Fensom, Anthony H., Higaki, Katsumi, Elleder, Milan, Lobel, Peter, Vanier, Marie T.
Publicado em 2001

Extending the Mannose 6-Phosphate Glycoproteome by High Resolution/Accuracy Mass Spectrometry Analysis of Control and Acid Phosphatase 5-Deficient Mice

Por Sleat, David E., Sun, Pengling, Wiseman, Jennifer A., Huang, Ling, El-Banna, Mukarram, Zheng, Haiyan, Moore, Dirk F., Lobel, Peter
Publicado em 2013

Effective Intravenous Therapy for Neurodegenerative Disease With a Therapeutic Enzyme and a Peptide That Mediates Delivery to the Brain

Por Meng, Yu, Sohar, Istvan, Sleat, David E, Richardson, Jason R, Reuhl, Kenneth R, Jenkins, Robert B, Sarkar, Gobinda, Lobel, Peter
Publicado em 2014

Analysis of Brain and Cerebrospinal Fluid from Mouse Models of the Three Major Forms of Neuronal Ceroid Lipofuscinosis Reveals Changes in the Lysosomal Proteome

Por Sleat, David E., Wiseman, Jennifer A., El-Banna, Mukarram, Zheng, Haiyan, Zhao, Caifeng, Soherwardy, Amenah, Moore, Dirk F., Lobel, Peter
Publicado no Mol Cell Proteomics (2019)