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Genetic modulation of apoptotic pathways fails to alter disease course in tripeptidyl-peptidase 1 deficient mice
Late-infantile neuronal ceroid lipofuscinosis (LINCL) is a fatal, incurable neurodegenerative disease of children caused by the loss of the lysosomal protein tripeptidyl peptidase 1 (TPP1). Previous studies have suggested that Bcl-2 dependent apoptotic pathways are involved in neuronal cell death in...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680787/ https://ncbi.nlm.nih.gov/pubmed/19429009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.01.072 |
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