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A role for NPC1 and NPC2 in intestinal cholesterol absorption – the hypothesis gutted

Dietary and biliary cholesterol are taken up by intestinal epithelial cells and transported to the endoplasmic reticulum. At the endoplasmic reticulum, cholesterol is esterified, packaged into chylomicrons and secreted into the lymph for delivery to the bloodstream. NPC1L1 (Niemann–Pick C1-like 1) i...

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Detalhes bibliográficos
Autor principal: Liscum, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049072/
https://ncbi.nlm.nih.gov/pubmed/17956226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071340
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