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A role for NPC1 and NPC2 in intestinal cholesterol absorption – the hypothesis gutted

Dietary and biliary cholesterol are taken up by intestinal epithelial cells and transported to the endoplasmic reticulum. At the endoplasmic reticulum, cholesterol is esterified, packaged into chylomicrons and secreted into the lymph for delivery to the bloodstream. NPC1L1 (Niemann–Pick C1-like 1) i...

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Bibliografske podrobnosti
Glavni avtor: Liscum, Laura
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049072/
https://ncbi.nlm.nih.gov/pubmed/17956226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071340
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