Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption

BACKGROUND & AIMS: The nuclear receptor subfamily 0 group B member 2 (NR0B2, also called SHP) is expressed at high levels in liver and intestine. Postprandial fibroblast growth factor 19 (human FGF19, mouse FGF15) signaling increases the transcriptional activity of SHP. We studied the functions...

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Veröffentlicht in:Gastroenterology
Hauptverfasser: Kim, Young-Chae, Byun, Sangwon, Seok, Sunmi, Guo, Grace, Xu, H. Eric, Kemper, Byron, Kemper, Jongsook Kim
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409196/
https://ncbi.nlm.nih.gov/pubmed/30521806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.11.061
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