Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption

BACKGROUND & AIMS: The nuclear receptor subfamily 0 group B member 2 (NR0B2, also called SHP) is expressed at high levels in liver and intestine. Postprandial fibroblast growth factor 19 (human FGF19, mouse FGF15) signaling increases the transcriptional activity of SHP. We studied the functions...

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Publicado no:Gastroenterology
Main Authors: Kim, Young-Chae, Byun, Sangwon, Seok, Sunmi, Guo, Grace, Xu, H. Eric, Kemper, Byron, Kemper, Jongsook Kim
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409196/
https://ncbi.nlm.nih.gov/pubmed/30521806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.11.061
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