FXR-induced lysine-specific histone demethylase, LSD1, reduces hepatic bile acid levels and protects the liver against bile acid toxicity

Bile acids (BAs) function as endocrine signaling molecules that activate multiple nuclear and membrane receptor signaling pathways to control fed-state metabolism. Since the detergent-like property of BAs causes liver damage at high concentrations, hepatic BA levels must be tightly regulated. BA hom...

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Detaylı Bibliyografya
Yayımlandı:Hepatology
Asıl Yazarlar: Kim, Young-Chae, Fang, Sungsoon, Byun, Sangwon, Seok, Sunmi, Kemper, Byron, Kemper, Jongsook Kim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480214/
https://ncbi.nlm.nih.gov/pubmed/25545350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27677
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